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Isolation of Lysozyme-Specific T Cell Clones That Discriminate between Native and Denatured Antigen

✍ Scribed by Fabrizio Manca; Vitalia Dessı́; Nilabh Shastri; Alan Oki; Mark Kaplan; Jessica Clarke; Alexander Miller; Eli E. Sercarz


Book ID
112238929
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
326 KB
Volume
154
Category
Article
ISSN
0008-8749

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## Isolation of antigen-specific T cell clones from nonresponder mice\* The mechanisms responsible for major histocompatibility complex (MHC)-linked unresponsiveness are still poorly understood. Here we examine the cellular events that follow when BIO.A mice are immunized with cow insulin, an antig