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Isolation of giant DNA fragments from flow-sorted human chromosomes

✍ Scribed by Shinsei Minoshima; Kazuhiko Kawasaki; Ryuichi Fukuyama; Masahiko Maekawa; Jun Kudoh; Nobuyoshi Shimizu

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
906 KB
Volume
11
Category
Article
ISSN
0196-4763

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Representational difference analysis (RDA) of a human glioblastoma xenograft resulted in the isolation of five tumour-associated homozygously deleted DNA fragments, all originating from chromosome 9, region p21. Subsequent analysis of a series of ten glioblastomas using the newly isolated RDA fragme