The purpose of this study was to determine the proportion of fetal nucleated red blood cells (NRBCs) among enriched NRBCs and to evaluate the effectiveness of enriching NRBCs in maternal blood using fluorescenceactivated cell sorting (FACS) to separate NRBCs. The origin of enriched NRBCs was determi
Isolation of fetal nucleated red blood cells from maternal blood
β Scribed by Li, Zou ;Xiaojing, Ye ;Keshu, Xu ;Jianwen, Zhu
- Publisher
- Springer-Verlag
- Year
- 2000
- Tongue
- English
- Weight
- 346 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0257-716X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Chorionic villus sampling (CVS) is an established invasive prenatal diagnostic method for the detection of fetal chromosome aberrations. In 1-2% the karyotype result of CVS is inconclusive and follow-up confirmation will be required. To avoid another invasive procedure we examined fetal nucleated re
We set out to ascertain the numbers of fetal cells that enter the maternal blood stream during pregnancy. Samples of 15-16 ml of whole blood were collected from 225 women--mostly 10-18 weeks pregnant--and then processed by charge flow separation, a novel method based on free flow electrophoresis in