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Isolation of detergent resistant microdomains from cultured neurons: detergent dependent alterations in protein composition

✍ Scribed by Ritchie Williamson; Andrew J Thompson; Mika Abu; Abdul Hye; Alessia Usardi; Steven Lynham; Brian H Anderton; Diane P Hanger


Book ID
115006523
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
611 KB
Volume
11
Category
Article
ISSN
1471-2202

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## Abstract Changes in the composition of cell fractions, and in particular of detergent‐resistant membranes (DRM) isolated from cultured rat cerebellar granule cells, were taken as possible changes in lipid raft composition during a signal transduction event. After activation of protein kinase C (