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Isolation of cyclic AMP and cyclic GMP by thin-layer chromatography. Application to assay of adenylate cyclase, guanylate cyclase, and cyclic nucleotide phosphodiesterase

โœ Scribed by James J. Keirns; Marcia A. Wheeler; Mark W. Bitensky


Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
750 KB
Volume
61
Category
Article
ISSN
0003-2697

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โœ Thomas F. J. Martin; Susan A. Ronning ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 715 KB

## Abstract GH pituitary cells have been widely utilized for studies of hormone response mechanisms. Studies reported here were motivated by the desirability of isolating characterized GH clones defective in cyclic AMP synthesis or action. Spontaneously occurring GH~1~ cell variants resistant to th