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Isolation of an IL-13-dependent subclone of the B9 cell line useful for the estimation of human IL-13 bioactivity

✍ Scribed by C.Labit-Le Bouteiller; R. Astruc; A. Minty; P. Ferrara; J.H. Lupker


Book ID
118902879
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
658 KB
Volume
181
Category
Article
ISSN
0022-1759

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A selected clone from an IL-2-dependent human T-cell line was persistently propagated in the presence of phorbol esters with the ability to activate protein kinase C (PKC), such as 12-0-tetradecanoylphorbol-I 3-acetate (TPA) or phorbol-12,1.3-dibutylate (PDBu). Thus, a TPA(PD6u)-dependent T-cell lin