Isolation of an HTLV-1-like retrovirus from patients with tropical spastic paraparesis
✍ Scribed by Jacobson, Steven; Raine, Cedric S.; Mingioli, Elizabeth S.; McFarlin, Dale E.
- Book ID
- 109752178
- Publisher
- Nature Publishing Group
- Year
- 1988
- Tongue
- English
- Weight
- 514 KB
- Volume
- 331
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/331540a0
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## Abstract The oncoprotein Tax was characterized genetically from a large cohort of human T‐cell lymphotropic virus type 1 (HTLV‐1) seropositive individuals from the most endemic region of HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) and HTLV‐1 infection in Argentina, the pr
## Abstract The human T‐cell lymphotropic virus type 1 (HTLV‐1) is the etiological agent of HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), a progressive disease causing paraparesis of the lower limbs. Only a minority of persons infected with HTLV‐1 develop HAM/TSP. Universal s