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Isolation of a temperature-sensitive dnaA mutant of Staphylococcus aureus

โœ Scribed by Nagamoto Murai; Kenji Kurokawa; Norikazu Ichihashi; Miki Matsuo; Kazuhisa Sekimizu


Book ID
109329081
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
133 KB
Volume
254
Category
Article
ISSN
0378-1097

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A cold sensitive dnaA mutant of E. coli
โœ Kellenberger-Gujer, G. ;Podhajska, A. J. ;Caro, L. ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Springer ๐ŸŒ English โš– 738 KB

A heat resistant mutant of E. coli dnaAts46 was isolated, which grows normally only at temperatures above 39 degrees. After a temperature shift from 42 degrees to 32 degrees the mutant overproduces DNA relative to protein. This is due to overinitiation of rounds of chromosome replication at low temp