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Isolation of a new type C retrovirus (HTLV) in primary uncultured cells of a patient with Sézary T-cell leukaemia

✍ Scribed by Poiesz, Bernard J.; Ruscetti, Francis W.; Reitz, Marvin S.; Kalyanaraman, V. S.; Gallo, Robert C.


Book ID
109724779
Publisher
Nature Publishing Group
Year
1981
Tongue
English
Weight
750 KB
Volume
294
Category
Article
ISSN
0028-0836

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Se-Ax is a continuous mature T-cell line that we have established from a patient with Sézary's syndrome. An important finding was that the Se-Ax cell line required human serum for initial growth. Here we show that transfer of the permanent cell line to a medium deficient of human serum induces produ