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Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant

✍ Scribed by Jaekwon Lee; Joseph R. Prohaska; Susan L. Dagenais; Thomas W. Glover; Dennis J. Thiele


Book ID
117519963
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
446 KB
Volume
254
Category
Article
ISSN
0378-1119

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A cDNA clone named L21 was isolated from L6 rat muscle cells by complementation of a yeast proline transport mutant. L21 cDNA has 2,268 bp and codes for a peptide of 228 amino acids with four potential transmembrane domains. The amino acid sequence of L21 shows no homology to any known proteins. Exp