The purpose of this study was to evaluate the protective effect of a new endotoxin analogue, monophosphoryl lipid A (MLA) in a rabbit model of myocardial ischemia/reperfusion and to show if this protection was mediated via synthesis of 70 kDa heat shock protein (HSP 70). Three groups of New Zealand
Isolation of a cDNA encoding a 70 kDa heat-shock cognate protein expressed in vegetative tissues ofArabidopsis thaliana
✍ Scribed by Shiuh-Hwan Wu; Chung Wang; Jychian Chen; Bai-Ling Lin
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 586 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0167-4412
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✦ Synopsis
A cDNA encoding a 70 kDa heat shock 'cognate' protein (hsc70) was isolated from Arabidopsis thaliana by using a rat hsc70 cDNA as probe. Sequence analysis demonstrated the conservation of functional domains and important amino acid residues among hsc70s in plants and animals. The expression of this gene was stress-inducible, and was found at a substantial level during normal growth in root, stem, leaf and flower tissues, but not in siliques. Multiple copies of this gene exist in the Arabidopsis genome.
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The purpose of this study was to evaluate the protective effect of a new endotoxin analogue, monophosphoryl lipid A (MLA) in a rabbit model of myocardial ischemia/reperfusion and to show if this protection was mediated via synthesis of 70 kDa heat shock protein (HSP 70). Three groups of New Zealand