Isolation, identification and determination of cyclophosphamide and two of its metabolites in urine of a multiple sclerosis patient by high pressure liquid chromatography and field desorption mass spectrometry

Determination of the metabolites of gest

Determination of the metabolites of gestrinone in human urine by high performance liquid chromatography, liquid chromatography/mass spectrometry and gas chromatography/mass spectrometry

✍ Yunje Kim; Yongkwan Lee; Myungsoo Kim; Yong-Hyeon Yim; Won Lee 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB 👁 2 views

Identification of carpronium chloride an

Identification of carpronium chloride and its metabolite in human urine by field desorption mass spectrometry using deuterium labelling

✍ Mitsuji Sano; Kazumi Ohya; Ryoji Ito 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 English ⚖ 459 KB 👁 2 views

Liquid–liquid extraction procedure for t

Liquid–liquid extraction procedure for trace determination of cyclophosphamide in human urine by high-performance liquid chromatography tandem mass spectrometry

✍ Cristina Sottani; Roberta Turci; Luigi Perbellini; Claudio Minoia 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 2 views

A sensitive, specific and accurate high performance liquid chromatography/ionspray-tandem mass spectrometry procedure (HPLC/MS/MS) has been developed to quantify cyclophosphamide in human urine from hospital personnel involved in drug preparation and administration of antineoplastic alkylating agent

Isolation of circulating metabolites in

Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy

✍ Hong Kim; Wenqing Feng; Tze-Ming Chan; Diane Rindgen; Matthew Bryant; Kathleen A 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB 👁 2 views

Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy One of the major components of modern drug discovery is the structu

Validation study of assay method for DX-

Validation study of assay method for DX-8951 and its metabolite in human plasma and urine by high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry

✍ Toshihiro Oguma; Tomomi Konno; Atsuhiro Inaba; Minoru Nakaoka 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB 👁 2 views

Determination of n-hexane metabolites by

Determination of n-hexane metabolites by liquid chromatography/mass spectrometry 2. Glucuronide-conjugated metabolites in untreated urine samples by electrospray ionization

✍ Paola Manini; Roberta Andreoli; Antonio Mutti; Enrico Bergamaschi; Wilfried M. A 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB 👁 2 views

A liquid chromatography atmospheric pressure electrospray mass spectrometry (ESI-LC/MS) system was evaluated for the identification and characterization of n-hexane conjugated metabolites (glucuronides) in untreated urine samples. Chromatography of glucuronides was obtained under ion-suppressed reve