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Isolation, characterisation and synthesis of a new quinidine metabolite

โœ Scribed by Theodor W. Guentert; John J. Daly; Sidney Riegelman


Book ID
113006372
Publisher
Springer-Verlag
Year
1982
Tongue
English
Weight
727 KB
Volume
7
Category
Article
ISSN
0378-7966

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Spiroepoxide 1 was prepared the new tricyclic dehydrorubanone 7, con-20 g scale. Reduction with NaBH, in the from quinidine and converted into 8taining the 4-oxa-7-azatricyclo[4.3.1 .037 ' 1-presence of CeCI, provided rubanols amino alcohol 3 (86% over two steps). decan-Zone core structure. Similarl