of the ceramide moiety is presumed to be (2S\*,3S\*,4R\*),
Isolation and Structure of Biologically Active Gangliosides from the Sea Cucumber Holothuria pervicax
β Scribed by Koji Yamada; Yasuo Harada; Yoshiteru Nagaregawa; Tomofumi Miyamoto; Ryuichi Isobe; Ryuichi Higuchi
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 383 KB
- Volume
- 1998
- Category
- Article
- ISSN
- 1434-193X
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β¦ Synopsis
Three ganglioside molecular species, HPG-8, HPG-3, and species. HPG-8 is a sulfated monosialo-ganglioside, while HPG-3 and HPG-1 are disialo-gangliosides possessing 2Η4-HPG-1, have been obtained from the polar fraction of the chloroform/methanol extract of the sea cucumber Holothuria linked tandem-type disialosyl moieties. These three gangliosides qualitative neuritogenic activity toward the rat pervicax. The structures of these gangliosides have been determined on the basis of chemical and spectroscopic pheochromocytoma cell line, PC-12 cells. evidence. They represent new ganglioside molecular
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