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Isolation and structure elucidation of vancoresmycin—a new antibiotic from Amycolatopsis sp. ST 101170

✍ Scribed by Cordula Hopmann; Michael Kurz; Mark Brönstrup; Joachim Wink; Dominique LeBeller

Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 163 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)02171-2

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✦ Synopsis

A new antibiotic, active against Gram-positive bacteria, has been isolated from the fermentation broth of the actinomycete Amycolatopsis sp. ST 101170. The structure of the compound named vancoresmycin, a tetramic acid derivative with a highly oxygenated long alkyl chain, was elucidated by extensive spectroscopic studies and derivatization.

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