✦ LIBER ✦

Isolation and structure elucidation of new salfredin-type metabolites from Crucibulum laeve DSM 1653 and DSM 8519

✍ Scribed by Tobias Neumann; Brigitte Schlegel; Peter Hoffmann; Stephan Heinze; Udo Gräfe

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 254 KB
Volume: 39
Category: Article
ISSN: 0233-111X
DOI: 10.1002/(sici)1521-4028(199912)39:5/6<357::aid-jobm357>3.0.co;2-8

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✦ Synopsis

New salfredin-type chromene and benzofurane metabolites ( ¤ were isolated from submerged cultures of the fungal strains Crucibulum laeve DSM 1653 and C. laeve DSM 8519. The structures were elucidated on the basis of UV-VIS spectroscopic, mass spectrometric and NMR spectroscopic evidence. The new metabolites are discussed as intermediates and shunt metabolites of the fungal aromatic pathway leading to A-, B-and C-type salfredins.