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Isolation and Structure Elucidation of Enniatins L, M1, M2, and N: Novel Hydroxy Analogs

✍ Scribed by Pornrapee Vongvilai; Masahiko Isaka; Prasat Kittakoop; Prasert Srikitikulchai; Palangpon Kongsaeree; Samran Prabpai; Yodhathai Thebtaranonth


Publisher
John Wiley and Sons
Year
2004
Tongue
German
Weight
203 KB
Volume
87
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Four new cyclohexadepsipeptides, enniatins L (1), M~1~ (2), M~2~ (3), and N (4), have been isolated from an unidentified fungus (BCC 2629), together with the known enniatins B (5), H (6), and I (7), MK1688 (8), and enniatin B~4~ (9). Compounds 14 are the first enniatin analogs with an OH group at the side chain of one of the 2‐hydroxycarboxylic acid residues. The structures of 14 were elucidated by spectroscopic means and by X‐ray crystallography.


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