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Isolation and stereostructure of aurilide, a novel cyclodepsipeptide from the Japanese sea hare Dolabella auricularia

โœ Scribed by Kiyotake Suenaga; Tsuyoshi Mutou; Takunobu Shibata; Takashi Itoh; Hideo Kigoshi; Kiyoyuki Yamada


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
251 KB
Volume
37
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


Aurilide (1)

, a new 26-membered cyclodepsipeptide, has been isolated from the Japanese sea hare Dolabella auricularia. The gross structure of I was established by spectroscopic analysis. The absolute stereostructure of I was determined by HPLC analysis of amino acid components and isoleucic acid obtained from acidic hydrolysis of I and by the enantioselective synthesis of the tris(pbromobenzoate) 3 derived from the dihydroxy acid moiety.


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