Isolation and sequence analysis of new peptaibol, boletusin, from Boletus spp.

✍ Scribed by Sang-Jun Lee; Woon-Hyung Yeo; Bong-Sik Yun; Ick-Dong Yoo

• Book ID: 101284138
• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 89 KB
• Volume: 5
• Category: Article
• ISSN: 1075-2617
• DOI: 10.1002/(sici)1099-1387(199908)5:8<374::aid-psc211>3.0.co;2-x

✦ Synopsis

A new peptaibol, boletusin, was isolated from the methanol extract of the fruiting body of the mushroom, Boletus spp. Sequential determination by positive FAB MS/MS showed that boletusin is a peptide consisting of 19 amino acids, with one acetylated N-terminus residue, phenylalanine, and a C-terminal amino alcohol, tryptophanol. This peptide showed antimicrobial activity against several Grampositive bacteria.