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Isolation and properties of the products of the covalent hydration of 4H-imidazoles

✍ Scribed by V. S. Kobrin; L. B. Volodarskii; L. A. Tikhonova; Yu. G. Putsykin

Book ID
112326487
Publisher
Springer US
Year
1973
Tongue
English
Weight
477 KB
Volume
9
Category
Article
ISSN
0009-3122

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The electrophilic properties of the 4H-imidazoles 1 and their protonated derivatives 2 permit the introduction of nucleophilic building blocks, as illustrated by reactions of 1 with selected amines. Depending on the nature of the amine and the substituents R 1 on the heterocycle 1, single (3) or dou