Isolation and identification of the hydrolytic degradation products of ranitidine hydrochloride
โ Scribed by Haywood, Phillip A.; Martin-Smith, Michael; Cholerton, Trevor J.; Evans, Michael B.
- Book ID
- 121188723
- Publisher
- Royal Society of Chemistry
- Year
- 1987
- Weight
- 485 KB
- Category
- Article
- ISSN
- 1472-7781
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๐ SIMILAR VOLUMES
Dyclonine hydrochloride, a local anesthetic, is known to degrade in aqueous media. In this paper, the isolation and characterization of two major degradation products, formed by heating of an aqueous solution of dyclonine hydrochloride for 2 weeks at 50 "C, are presented. The proton and carbon-13 n
A study of the degradation kinetics of gemcitabine hydrochloride (2ะ-deoxy-2ะ,2ะ-difluorocytidine) in aqueous solution at pH 3.2 was conducted. The degradation of gemcitabine followed pseudo first-order kinetics, and rate constants were determined at four different temperatures. These rates were use