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Isolation and identification of S(+)-3-hydroxyisobutyric acid in the urine of rats loaded with isobutyric acid

✍ Scribed by Amster, Jon; Tanaka, Kay

Book ID: 122102435
Publisher: Elsevier Science
Year: 1979
Tongue: English
Weight: 137 KB
Volume: 585
Category: Article
ISSN: 0304-4165
DOI: 10.1016/0304-4165(79)90196-X

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## Abstract After the intraperitoneal administration of high doses of ^14^C‐ and ^3^H‐labelled retinoic acid (**1**) to rats three major urinary metabolites have been isolated in microgram amounts by use of column, thin‐layer and high‐pressure liquid chromatography. Their structures were elucidated