Isolation and identification of a metabolite of methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate in rat urine
β Scribed by Gardiner, John A.; Brantley, Richard K.; Sherman, Henry.
- Book ID
- 127130925
- Publisher
- American Chemical Society
- Year
- 1968
- Tongue
- English
- Weight
- 235 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0021-8561
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The metabolic fate of 2-ethylhexyl diphenyl phosphate (EHDPP) was studied in male rats. Orally administered 14C-EHDPP was rapidly absorbed and about 80% of the radioactivity was excreted in the urine and feces in the first 24 h. By 7 days, 48% and 52% of the radioactivity was recovered in urine and
The structure of a new metabolite T-2 toxin (iso-TC-1) has been established as 3,15-diacetoxy-4-hydroxy-8(3-methyl-3'-hydroxy-butyryloxy)-lZ,l3-epoxytrichothec-9-ene. The compound is an isomer of TC-1 (a recently isolated T-2 derivative) in which the hydroxy and acetoxy groups at the C-3 and C-4 pos