It was demonstrated that rapamycin is metabolized in vitro by pig liver microsomes under the inÑuence of the cytochrome P450-dependent mixed function oxygenase system to a rapamycin tris-epoxide metabolite, as demonstrated by electrospray tandem mass spectrometry . The in vitro immunosuppressive act
Isolation and identification by FAB mass spectrometry and NMR spectroscopy of a demethylated metabolite of FK506 from erythromycin-induced rabbit liver microsomes
✍ Scribed by G. Lhoëst; N. Maton; R. Verbeeck
- Book ID
- 118961311
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 366 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0031-6865
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