𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Isolation and identification by 2D NMR of two new complex saponins from Michrosechium helleri

✍ Scribed by Ismael León; Raul G. Enríquez; Stewart McLean; William F. Reynolds; Margaret Yu

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
240 KB
Volume
36
Category
Article
ISSN
0749-1581

No coin nor oath required. For personal study only.

✦ Synopsis

Two complex saponins, amole F and G, were characterized and their spectra were assigned using only 1D and 2D 1H and NMR methods. Amole F and G have seven and six monosaccharides, respectively, linked to the triterpene aglycone bayogenin. In addition to standard 2D methods, a series of TOCSY spectra with di †erent mixing times and a high-resolution coupled HSQC spectrum were particularly useful for assigning the monosaccharide units. It is concluded that saponins of this complexity are approaching the limit of structural complexity that can be solved by NMR alone, although the limit might be pushed further by access to ultra-high Ðeld NMR spectrometers.

📜 SIMILAR VOLUMES

Structural elucidation of four new furos
Structural elucidation of four new furostanol saponins from Tupistra chinensis by 1D and 2D NMR spectroscopy
✍ Kun Zou; Jun-zhi Wang; Zhi-yong Guo; Ming Du; Jun Wu; Yuan Zhou; Fei-jun Dan; Ch 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 111 KB 👁 1 views

## Abstract Four new furostanol saponins (1–4), two pairs of diastereoisomers, were isolated from methanolic extracts of __T__upistra chinensis rhizomes and their structures were assigned from ^1^H and ^13^C NMR spectra, DEPT, and by 2D COSY, NOESY, HMQC, and HMBC experiments. Copyright © 2008 John

New bitter saponins from the bark of Col
New bitter saponins from the bark of Colubrina elliptica: 1H and 13C assignments by 2D NMR spectroscopy
✍ Winston F. Tinto; William F. Reynolds; Compton E. Seaforth; Shaliza Mohammed; An 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 362 KB

## Abstract Three new bitter saponins, designated mabioside A, B and C, were isolated from the bark of __Colubrina elliptica__ and were determined to be 3‐__O__‐[α‐JL‐rhamnopyranosy]‐(1 → 6)‐β‐D‐glucopyranosyl‐15‐__O__‐[β‐D‐ glucopyranosyl] mabiogenin, 3‐__O__‐[α‐L‐rhamnopyranosy]‐(1 → 6)‐[β‐D‐gluc

Isolation and structural determination o
Isolation and structural determination of sorbinols A and B, new triterpenes from Sorbus cashmariana, by 1D and 2D NMR spectroscopy
✍ Mehdi Hassan Kazmi; Ejaz Ahmed; Saira Hameed; Abdul Malik; Muhammad Ashraf 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 110 KB 👁 1 views

## Abstract Two new pentacyclic triterpenes, sorbinols A (1) and B (2) have been isolated from the ethyl acetate fraction of __Sorbus cashmariana__ and their structures assigned from ^1^H and ^13^C NMR spectra, DEPT and by 2D COSY, NOE, HMQC and HMBC experiments. Both 1 and 2 showed moderate inhibi

Structure elucidation of two new unusual
Structure elucidation of two new unusual monoterpene glycosides from Euphorbia decipiens, by 1D and 2D NMR experiments
✍ Ozlem Demirkiran; Gulacti Topcu; Javid Hussain; Viqar Uddin Ahmad; M. Iqbal Chou 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB

## Abstract Two new unusual monoterpene glycosides, (__Z__)‐3,6‐dimethyl‐3‐(β‐D‐__O__‐glucosylmethylene)cyclohept‐4‐ene‐1‐one (1) and 3,6‐dimethyl‐3‐(β‐D‐__O__‐glucosylmethylene)cycloheptanone (2) have been isolated along with five known compounds, 3‐hydroxy‐4‐methoxybenzoic acid, 6,7‐dihydroxycoum

Structure determination of salisomide an
Structure determination of salisomide and salisoflavan, two new secondary metabolites from Salsola imbricata, by 1D and 2D NMR spectroscopy
✍ Muhammad Saleem; Naseem Akhter; Muhammad Shaiq Ali; Mamona Nazir; Naheed Riaz; M 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 91 KB

## Abstract Chromatographic analysis of the alcoholic extract from __Salsola imbricata__ yielded two new secondary metabolites, salisomide (1) and salisoflavan (2). Their structures were established with the help of spectroscopic techniques including COSY, HMQC and HMBC NMR experiments. Copyright ©

Isolation, identification and immunosupp
Isolation, identification and immunosuppressive activity of a new IMM-125 metabolite from human liver microsomes. identification of its cyclophilin A-IMM-125 metabolite complex by nanospray tandem mass spectrometry
✍ Lhoëst, G. J. J.; de Jong, A. P. J. M.; Meiring, H. D.; Maton, N.; Latinne, D.; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 296 KB 👁 2 views

The isolation from human liver microsomes and identiÐcation by electrospray mass spectrometry and tandem mass spectrometry of a new metabolite of IMM-125 resulting from the biotransformation of the amino acid 1 vinylic methyl group to a carboxylic acid, called the IMM-125-COOH metabolite, is describ