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Isolation and Clonal Analysis of Human Epidermal Keratinocyte Stem Cells in Long-Term Culture

✍ Scribed by Sandra Papini; Denise Cecchetti; Daniela Campani; Wendy Fitzgerald; Jean Charles Grivel; Silvia Chen; Leonid Margolis; Roberto P. Revoltella

Book ID
111845884
Publisher
AlphaMed Press
Year
2003
Tongue
English
Weight
557 KB
Volume
21
Category
Article
ISSN
1066-5099

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## Abstract Human embryonic stem cells (hESCs) during long‐term culture acquire chromosomal changes similar to those occurring in tumorigenesis. This was raised concerns about the progression from hESCs to malignant cells. This study aimed to investigate the changes in chromosomes, cell phenotype,