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Isolation and Characterization of the Mouse PDGF β-Receptor Promoter

✍ Scribed by A.E. Ballagi; A. Ishizaki; J.O. Nehlin; K. Funa

Book ID
115576573
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
513 KB
Volume
210
Category
Article
ISSN
0006-291X

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## Abstract Herein, we show that both exogenously transfected and endogenously activated p53 repress promoter activity and expression of PDGFRB. p53 binds the proximal promoter containing the CCAAT motif as examined by EMSA and chromatin immunoprecipitation. However, gradual induction of p53 in tet