𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Isolation and Characterization of Schwann Cells from Neurofibromatosis Type 2 Patients

✍ Scribed by C. Rosenbaum; L. Kluwe; V.F. Mautner; R.E. Friedrich; H.W. Müller; C.O. Hanemann

Book ID
115641426
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
428 KB
Volume
5
Category
Article
ISSN
0969-9961

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Voltage-dependent membrane currents of c
Voltage-dependent membrane currents of cultured human neurofibromatosis type 2 Schwann cells
✍ Martin Kamleiter; C. Oliver Hanemann; Lan Kluwe; Claudia Rosenbaum; Susanne Wosc 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB 👁 1 views

Previous experimental observations indicate that inhibition of voltage-dependent K+ currents suppresses proliferation of normal Schwann cells. In the present study we tested the opposite relationship, i.e., whether Schwann cells from tumors with abnormally high rates of proliferation would have an i

Merlin, the neurofibromatosis type 2 gen
Merlin, the neurofibromatosis type 2 gene product, and ?1 integrin associate in isolated and differentiating Schwann cells
✍ Obremski, Valerie J. ;Hall, Ashley M. ;Fernandez-Valle, Cristina 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 477 KB 👁 2 views

Neurofibromatosis type 2, a disease characterized by the formation of multiple nervous system tumors, especially schwannomas, is caused by mutation in the gene-encoding merlin/schwannomin. The molecular mechanism by which merlin functions as a tumor suppressor is unknown, but is hypothesized to invo

c-Kit receptor expression in normal huma
c-Kit receptor expression in normal human Schwann cells and Schwann cell lines derived from neurofibromatosis type 1 tumors
✍ Ian Dang; Julie K. Nelson; George H. DeVries 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 181 KB 👁 1 views

The growth factor receptor c-Kit has several well-characterized functions during the development of numerous cell types, including red blood cells, mast cells, and melanocytes. Its role in Schwann cells has been described in transformed cells derived from malignant peripheral nerve sheath tumors fro

Characterization of polyol pathway in sc
Characterization of polyol pathway in schwann cells isolated from adult rat sciatic nerves
✍ Takeshi Suzuki; Kuniharu Mizuno; Satomi Yashima; Kazuo Watanabe; Kaori Taniko; T 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 380 KB 👁 2 views

To elucidate the molecular mechanisms underlying the development of diabetic neuropathy, we isolated the Schwann cells from the sciatic nerves of adult rats and characterized the polyol pathway activity. Despite the presence of aldose reductase (AR) activity, no accumulation of sorbitol was observed