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Isolation and Characterization of Proinsulin-Producing Medullary Thymic Epithelial Cell Clones

✍ Scribed by Palumbo, M. O.; Levi, D.; Chentoufi, A. A.; Polychronakos, C.

Book ID
121361482
Publisher
American Diabetes Association
Year
2006
Tongue
English
Weight
313 KB
Volume
55
Category
Article
ISSN
0012-1797

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## Abstract Thymic epithelial cells (TEC) form the structural and functional microenvironment necessary for the establishment and quality control of the T cell repertoire. In addition, they provide an ectopic source of numerous tissue‐restricted antigens (TRA), a feature called promiscuous gene exp