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Isolation and characterization of pharmaceutical grade human pentraxins, serum amyloid P component and C‐reactive protein, for clinical use

✍ Scribed by Mark B. Pepys; J. Ruth Gallimore; Joanne Lloyd; Zhanhong Li; David Graham; Graham W. Taylor; Stephan Ellmerich; Palma P. Mangione; Glenys A. Tennent; Winston L. Hutchinson; David J. Millar; Gary Bennett; John More; David Evans; Yogesh Mistry; Stephen Poole; Philip N. Hawkins


Book ID
119298654
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
775 KB
Volume
384
Category
Article
ISSN
0022-1759

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Structural basis of ligand specificity i
✍ Halina Mikolajek; Simon E. Kolstoe; Valerie E. Pye; Palma Mangione; Mark B. Pepy 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 573 KB

## Abstract The normal physiological roles of the phylogenetically conserved human plasma proteins C‐reactive protein (CRP) and serum amyloid P component (SAP) are not known. Novel drugs targeting their ligand specificities are in clinical development as both proteins have significant pathophysiolo