The isolation and characterization of human monoclonal antibodies (humAbs) against the hepatitis C Virus (HCV) glycoproteins E1 and E2 are described. B-cells from blood donors with anti-HCV were transformed with Epstein-Barr virus. The supernatants of the resulting lymphoblastoid clones were screene
Isolation and characterization of novel human monoclonal antibodies possessing neutralizing ability against rabies virus
β Scribed by Takashi Matsumoto; Kentaro Yamada; Kazuko Noguchi; Kantou Nakajima; Kenzo Takada; Pakamatz Khawplod; Akira Nishizono
- Book ID
- 108578456
- Publisher
- Center for Academic Publications, Japan
- Year
- 2010
- Tongue
- English
- Weight
- 348 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0385-5600
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## Abstract Therapeutic antibodies against varicellaβzoster virus (VZV) were isolated from a combinatorial library of human antibodies using a phageβdisplay system. Purified gH:gL was used to screen the library, and approximately 300 clones were isolated. Eight kinds of Fabβcp3βfused molecules (clo