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Isolation and characterization of ICO-160 monoclonal antibodies to CD95(Fas/APO-1) antigen that mediates apoptosis

✍ Scribed by E. R. Polosukhina; T. N. Zabotina; Yu. V. Shishkin; Z. G. Kadagidze; A. Yu. Baryshnikov


Publisher
Springer US
Year
1998
Tongue
English
Weight
224 KB
Volume
125
Category
Article
ISSN
0007-4888

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## Abstract It is important for more effective gene therapies to clarify the mechanisms by which cDNA integrated into cells can maintain or lose its function __in vivo__. We evaluated genetic and epigenetic events leading to alternation of the introduced CD95 (Fas/Apo‐1) gene as a model of gene the