Isolation and characterization of frameshift mutations in the lac operon
β Scribed by Newton, Austin
- Book ID
- 122595455
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- English
- Weight
- 927 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0022-2836
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We isolated strains of Escherichia coli K 12 in which the lac structural genes were fused to the structural genes of the guaBA operon. These strains were used to isolate regulatory mutations that increased the expression of the guaBA operon under normal repressing conditions as compared to the wild