Isolation and characterization of anArabidopsis thalianagene for the 54 kDa subunit of the signal recognition particle

✍ Scribed by Jon T. Lindstrom; Boyang Chu; Faith C. Belanger

• Publisher: Springer
• Year: 1993
• Tongue: English
• Weight: 602 KB
• Volume: 23
• Category: Article
• ISSN: 0167-4412
• DOI: 10.1007/bf00042359

✦ Synopsis

The first step in the routing of newly synthesized proteins into the secretory pathway is the binding of the nascent signal sequence to the signal recognition particle. The mammalian signal recognition particle is a complex consisting of 6 proteins and a single 7S RNA molecule. Signal recognition particlelike complexes have been described from wheat and maize but none of the protein components have yet been described from any plant species. Here we report the cloning and characterization of an Arabidopsis thaliana gene encoding the 54 kDa protein subunit of the signal recognition particle. This is the first report of a SRP-54 sequence for any plant species and the first genomic sequence for any multicellular organism.