Isolation and Characterization of a Tumor Cell Surface Antigen from Spontaneously Transformed BALB/c Mouse Fibroblasts
โ Scribed by Arthur R. Kamm and William J. Grimes
- Book ID
- 123655427
- Publisher
- National Academy of Sciences
- Year
- 1978
- Tongue
- English
- Weight
- 935 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/68868
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๐ SIMILAR VOLUMES
A rabbit antiserum (A2) directed against the detergent-solubilized fraction of the simian virus 40-transformed mouse embryo fibroblast cell line VLM detects common antigens in primary cell cultures from BALB/c mouse embryos and in transformed cell lines from various species. Positively reacting cell
## Abstract A solubilization technique employing 0.5% Triton Xโ100 was developed to obtain both SV40 virus (SV40)โinduced tumorโspecific surface antigen(s) (TSSA) from SV40โtransformed mouse cells, as determined by a serumโmediated microcytolytic assay, and tumorโspecific transplantation antigen(s)