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Isolation and characterization of a Tie2 kinase inhibitory sulfated triterpenoid from a green alga of the Tuemoya genus: complete assignment of the 1H and 13C spectra of a sulfated triterpenoid Tie2 kinase inhibitor

✍ Scribed by Jason A. Clement; Bing-Nan Zhou; Randall K. Johnson; David G. I. Kingston


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
92 KB
Volume
41
Category
Article
ISSN
0749-1581

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✦ Synopsis


Abstract

Bioassay‐guided fractionation of an extract of a Tuemoya sp., using an assay for inhibitors of the enzyme Tie2 kinase, afforded a mixture of the sulfated cycloartanol triterpenoids 1 and 2. We report the full ^1^H and ^13^C NMR spectral assignments for 1 and the ^13^C NMR spectral assignments for 2. Copyright © 2003 John Wiley & Sons, Ltd.