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Isolation and characterization of a novel cDNA, UBAP1, derived from the tumor suppressor locus in human chromosome 9p21–22

✍ Scribed by Jun Qian; Jianbo Yang; Xiaohui Zhang; Bicheng Zhang; Jieru Wang; Ming Zhou; Ke Tang; Weifang Li; Zhaoyang Zeng; Xiaorong Zhao; Shourong Shen; Guiyuan Li

Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
214 KB
Volume
127
Category
Article
ISSN
1432-1335

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The long arm of chromosome 9 is thought to contain one or more putative tumor suppressor genes that are mutated in squamous cell carcinomas. This region shows frequent loss of heterozygosity (LOH) in carcinomas arising in several developmentally related tissues, including the esophagus, head and nec