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Isolation and characterization of a major adduct between mitomycin C and DNA

✍ Scribed by Tomasz, Maria.; Lipman, Roselyn.; McGuinness, Brian F.; Nakanishi, Koji.

Book ID
126424736
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
601 KB
Volume
110
Category
Article
ISSN
0002-7863

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## Abstract A bulky DNA adduct (Spot 1) was previously detected in normal adjacent breast tissues of 41% (36/87) of women with breast cancer and in none (0/29) of the noncancer controls by ^32^P‐postlabeling. To characterize this adduct, it was chromatographically compared with DNA adduct profiles