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Isolation and characterization of a glycine transport mutant in an established mammalian cell line, CHO(PEOT/1)

✍ Scribed by Margaret Fairgrieve; James M. Mullin; Anne H. Dantzig; Carolyn W. Slayman; Edward A. Adelberg


Book ID
112557663
Publisher
Springer
Year
1987
Tongue
English
Weight
538 KB
Volume
13
Category
Article
ISSN
1572-9931

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## Abstract A mutant (A204) of Chinese hamster ovary cells (CHO‐K1), which is deficient in dihydroorotate (DHO) dehydrogenase (E.C. 1.3.3.1) activity, has been isolated by a replica plating procedure. The mutant does not show a requirement for exogenously added pyrimidines. Examination of intact ce