By merging two efficient technologies, bivariate flow sorting of human metaphase chromosomes and a recombination-based assay for sequence complexity, we isolated 28 cloned DNA segments homologous to loci on human chromosome 21. Subregional mapping of these DNA segments with a somatic cell hybrid pan
โฆ LIBER โฆ
Isolation and characterization of a DNA fragment containing various kinds of repetitive sequences located on human chromosome 21
โ Scribed by Ryoji Yao; David Patterson; Kazukiyo Onodera
- Publisher
- Nature Publishing Group
- Year
- 1993
- Tongue
- English
- Weight
- 1007 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1435-232X
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A genomic 38 kbp segment on the c1750 cosmid clone containing the cdc2 gene, located in the left arm of chromosome II from Schizosaccharomyces pombe, was sequenced. The segment was found to have ยฎve previously known genes, pht1, cdc2, his3, act1 and mei4. Among 11 coding sequences (CDSs) predicted b