Isolation amd partial characterization of the most immunologically reactive antigen from mycobacterium tuberculosis h37ra culture filtrate

Expression, purification, and characteri

Expression, purification, and characterization of protective MPT64 antigen protein and identification of its multimers isolated from nontoxic Mycobacterium tuberculosis H37Ra

✍ Teng-Ping J. Chu; Jeu-Ming P. Yuann 📂 Article 📅 2011 🏛 Portland Press 🌐 English ⚖ 223 KB

## Abstract MPT64, a secreted protein of __Mycobacterium tuberculosis__ (MTB), stimulates the immune reactions within cells and is a protective antigen that is lost by the bacilli Calmette–Guérin (BCG) vaccine during propagation. To minimize the toxicity caused by MTB, we used the __MPT64__ gene en