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Isolates and their potential use in complex gene mapping efforts

โœ Scribed by Teppo Varilo; Leena Peltonen

Book ID
116504884
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
261 KB
Volume
14
Category
Article
ISSN
0959-437X

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The transcription start sites of many genes are associated with CpG-rich DNA regions (CpG islands) containing clusters of rare cutting, methylation-sensitive restriction enzyme sites [Bird, 1986]. To detect gene sequences from human chromosome 21, we have screened cloned DNA fragments from a chromos