Isolated uveal tuberculoma masquerading as an intraocular tumor in an immunocompetent patient—a clinical-pathologic study with diagnosis by PCR
✍ Scribed by Eduardo F. Marback; Epaminondas de Souza Mendes; Ricardo D. Chagas Oliveira; Jignesh G. Parikh; Narsing A. Rao
- Book ID
- 107650139
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- English
- Weight
- 326 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1869-5760
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✦ Synopsis
Purpose
The aim of this article is to report a case of uveal tuberculoma simulating an intraocular tumor in which the diagnosis was only possible by polymerase chain reaction (PCR) analysis.
Method
This is a case report.
Results
A36-year-old male presented with a progressive growing intraocular tumor and no history or positive test for other systemic disease. The eye eventually turned blind and painful and was enucleated. Histopathologic analysis revealed a granulomatous reaction and caseation necrosis but failed to identify any causative microorganisms. Final tuberculosis diagnosis was only possible by quantitative PCR.
Conclusion
Isolated uveal tuberculoma can present in an otherwise healthy patient with negative systemic tuberculosis evaluation. PCR can be used to confirm tuberculosis when other methods have failed.