Isolated limb perfusion in locally advanced cutaneous melanoma
โ Scribed by Carlo Riccardo Rossi; Mirto Foletto; Pierluigi Pilati; Simone Mocellin; Mario Lise
- Book ID
- 114481250
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 104 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0093-7754
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๐ SIMILAR VOLUMES
Introduction: Two to three percent of the patients with extremity melanoma develop in-transit metastases in the course of their disease. When local treatments fail, isolated limb perfusion (ILP) is a reasonable option, but is generally only applied to patients without evidence of distant metastases.
A hazard of regional perfusion for melanoma is incomplete isolation, resulting in leakage of the cytostatic drug into the systemic circulation. Data were analysed retrospectively on 438 melphalan perfusions performed f o r melanoma of the extremities during the period [1978][1979][1980][1981][1982][