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Isoform-specific Regulation of Adenylyl Cyclase by Oxidized Catecholamines

โœ Scribed by Toshiaki Ebina; Yoshiyuki Toya; Naoki Oka; Carsten Schwencke; Jun-ichi Kawabe; Yoshihiro Ishikawa


Book ID
115632389
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
359 KB
Volume
29
Category
Article
ISSN
0022-2828

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Regulation of adenylyl cyclase isoforms
โœ Toshiaki Ebina; Yoshiyuki Toya; Jun-ichi Kawabe; Yoshihiro Ishikawa ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 126 KB

We examined the effect of n-alkanols on adenylyl cyclase isoforms (types II and V) overexpressed in insect cells. Ethanol stimulated the type II isoform but not the type V isoform. Ethanol stimulated type II adenylyl cyclase greater than GTPgS, and the treatment of the membrane with GDPbS or cholera