๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric glioma

โœ Scribed by Aditya Raghunathan; Adriana Olar; Hannes Vogel; John R. Parker; Susan C. Coventry; Robert Debski; Constance T. Albarracin; Kenneth D. Aldape; Daniel P. Cahill III; Suzanne Z. Powell; Gregory N. Fuller


Book ID
119188640
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
770 KB
Volume
16
Category
Article
ISSN
1532-8198

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


IDH1 mutations at residue p.R132 (IDH1R1
โœ Fonnet E. Bleeker; Simona Lamba; Sieger Leenstra; Dirk Troost; Theo Hulsebos; W. ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 196 KB

Systematic sequence profiling of the Glioblastoma Multiforme (GBM) genome has recently led to the identification of somatic mutations in the isocitrate dehydrogenase 1 (IDH1) gene. Interestingly, only the evolutionarily conserved residue R132 located in the substrate binding site of IDH1 was found m