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Isochromosome of a deleted 20q may be a relatively common abnormality in myeloid malignancies

✍ Scribed by Azra H. Ligon; Daniel J. DeAngelo; Leonard Atkins; Paola Dal Cin


Book ID
113512692
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
197 KB
Volume
162
Category
Article
ISSN
0165-4608

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## Abstract Deletion of the long arm of one chromosome 20 (del(20q)) is a well‐recognized abnormality in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) and is presumed to cause loss of a tumor suppressor gene at 20q12. In a previously published series of MDS and AML cases, which h