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ISOCHROMOSOME 7q IS RESTRICTED TO THE LYMPHOID LINEAGE IN T CELL ACUTE LYMPHOBLASTIC LEUKAEMIA

✍ Scribed by Toshiyuki Yamada; Jeffrey M. Craig; Lorna M. Secker-Walker


Book ID
114712051
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
256 KB
Volume
75
Category
Article
ISSN
0007-1048

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HSB-2 is a cell line derived from a patient who had T-cell acute lymphoblastic leukemia (T-cell ALL) with a t ( 1;7)(p34;q34). We used a genomic probe from the T-cell receptor beta (TCRB) locus (7q34) t o identify DNA rearrangements in HSB-2. Two rearranged Bglll DNA fragments were cloned, and one o