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Isochromosome 5p and related anomalies: a novel recurrent chromosome abnormality in myeloid disorders

✍ Scribed by Angèle Herry; Nathalie Douet-Guilbert; Frédéric Morel; Marie-Josée Le Bris; Nadia Guéganic; Christian Berthou; Marc De Braekeleer

Book ID: 113513755
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 103 KB
Volume: 200
Category: Article
ISSN: 0165-4608
DOI: 10.1016/j.cancergencyto.2010.04.006

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## Abstract Gene amplification is a rare phenomenon in acute leukemia, but recently amplification of specific chromosome bands containing genes rearranged in leukemia‐specific balanced chromosome translocations has been reported in a few cases. We detected duplication or amplification of chromosome