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Isochromosome 17q in primitive neuroectodermal tumors of the central nervous system

✍ Scribed by Dr. Jaclyn A. Biegel; Lucy B. Rorke; Roger J. Packer; Leslie N. Sutton; Luis Schut; Kathy Bonner; Beverly S. Emanuel


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
705 KB
Volume
1
Category
Article
ISSN
1045-2257

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πŸ“œ SIMILAR VOLUMES


Isochromosome 17q demonstrated by interp
✍ Jaclyn A. Biegel; Lucy B. Rorke; Anna J. Janss; Leslie N. Sutton; Annette H. Par πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 842 KB

## Abstract We previously reported an i(17q) as a non‐random finding in childhood primitive neuroectodermal tumors (PNETs) of the central nervous system. In the present study, we describe a two‐color interphase fluorescence in situ hybridization (FISH) assay for detection of chromosome 17 abnormali

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We have shown that an i(17q) is the most frequent abnormality in central nervous system primitive neuroectodermal tumors (PNETs; medulloblastoma), implicating the presence of a tumor suppressor gene which maps to 17p. In the present study, we investigated whether the deletion of chromosome arm 17p t

Mutation analysis and loss of heterozygo
✍ Irene Slavc; Ignacio R. Rodriguez; Krzysztof Mazuruk; Gerald J. Chader; Jaclyn A πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 120 KB πŸ‘ 2 views

Deletion of 17p is the most frequent abnormality observed in central nervous system (CNS) primitive neuroectodermal tumors (PNETs), implicating the presence of a tumor suppressor gene which maps to 17p. The gene for pigment epitheliumderived factor (PEDF) has been cloned and mapped to 17p13. PEDF be

Primitive neuroectodermal tumors in the
✍ Walter J. Hader; Katerina Drovini-Zis; John A. Maguire πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 224 KB πŸ‘ 2 views

## Abstract ## BACKGROUND Radiation induced intracranial neoplasms are uncommon but well described and include gliomas, meningiomas, and sarcomas. The development of primitive neuroectodermal tumors (PNETs) following prophylactic craniospinal irradiation has been infrequently reported previously.